Wagholikar KB, Mandel JC, Klann JG, Wattanasin N, Mendis M, Chute CG, Mandl KD, Murphy SN. SMART-on-FHIR implemented over i2b2 Journal of the American Medical Informatics Association. Available online 6 June 2016. (doi:

Mandel JC, Kreda DA, Mandl KD, Kohane IS, Ramoni RB. SMART on FHIR: a standards-based, interoperable apps platform for electronic health recordsJournal of the American Medical Informatics Association. Available online 17 February 2016. (doi: 10.1093/jamia/ocv189 .)

Mandl KD, Mandel JC, Kohane IS. Driving Innovation in Health Systems through an Apps-Based Information EconomyCell Systems. Available online 11 June 2015. (doi: 10.1016/j.cels.2015.05.001.)

Mandl KD, Kohane IS. Federalist principles for healthcare data networks. Nature Biotechnology 33, 360–363 (2015). doi: 10.1038/nbt.3180

Alterovitz G, et al. SMART on FHIR Genomics: Facilitating standardized clinico-genomic apps. J Am Med Inform Assoc 2015;0:1–6. doi: 10.1093/jamia/ocv045, Brief Communication.

Mandl KD. Ebola in the United States: EHRs as a Public Health Tool at the Point of Care. JAMA. Published online October 20, 2014. (doi: 10.1001/jama.2014.15064.)

Sunyaev A, Dehling T, Taylor PL, Mandl KD. Availability and quality of mobile health app privacy policies. J Am Med Inform Assoc. Published Online First: 21 August 2014 (doi: 10.1136/amiajnl-2013-002605).

D’Amore JD, Mandel JC, Kreda DA, et al. Are Meaningful Use Stage 2 certified EHRs ready for interoperability? Findings from the SMART C-CDA Collaborative. J Am Med Inform Assoc. Published Online First: doi: 10.1136/amiajnl-2014-002883

Klann JG, McCoy AB, Wright A, Wattanasin N, Sittig DF, Murphy SN. Health Care Transformation Through Collaboration on Open-Source Informatics Projects: Integrating a Medical Applications Platform, Research Data Repository, and Patient Summarization. Interact J Med Res 2013;2(1):e11 (doi: 10.2196/ijmr.2454).

Kohane, I. S., and Mandl, K. D. Escaping the EHR Trap — The Future of Health IT [PDF]. N Engl J Med 2012 Jun 14;366(24):2240-2.

Mandl KD, Mandel JC, Murphy SN, Bernstam EV, Ramoni RL, Kreda DA, McCoy JM, Adida B, Kohane IS. The SMART Platform: early experience enabling substitutable applications for electronic health records [PDF]. J Am Med Inform Assoc. 2012 Jul-Aug;19(4):597-603. (doi: 10.1136/amiajnl-2011-000622)

Murphy, S. N., Weber, G., Mendis, M., Gainer, V., Chueh, H. C., Churchill, S., and Kohane, I. Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2). J Am Med Inform Assoc 2010;17:124-30

Weitzman E.R., Kaci, L., and D., Mandl K. Sharing Medical Data for Health Research: The Early Personal Health Record Experience. J Med Internet Res 2010;e14

Weber, G. M., Murphy, S. N., McMurry, A. J., Macfadden, D., Nigrin, D. J., Churchill, S., and Kohane, I. S. The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories. J Am Med Inform Assoc 2009;624-30

Weitzman, E. R., Kaci, L., and Mandl, K. D. Acceptability of a personally controlled health record in a community-based setting: implications for policy and design. J Med Internet Res 2009;e14

Kohane IS,  Mandl KD, Clayton C, Chueh H, Frisse M, Kibbe D. Ten Principles for Fostering Development of an “iPhone-like” Platform for Healthcare Information Technology [PDF].

Kohane IS. Substitutability: Why, What and How? [PDF] Oct 5, 2009

Adida B. Open and Safe HIT Platforms [PDF] Sep 21, 2009

Mandl KD, Kohane IS. No small change for the health information economy. N Engl J Med. 2009 Mar 26;360(13):1278-81

Mandl, K. D. and Kohane, I. S. Tectonic shifts in the health information economy. N Engl J Med 2008;1732-7

Halamka, J. D., Mandl, K. D., and Tang, P. C. Early experiences with personal health records. J Am Med Inform Assoc 2008;1-7

Bourgeois, F. T., Simons, W. W., Olson, K., Brownstein, J. S., and Mandl, K. D. Evaluation of influenza prevention in the workplace using a personally controlled health record: randomized controlled trial. J Med Internet Res 2008;e5

Bourgeois, F. C., Taylor, P. L., Emans, S. J., Nigrin, D. J., and Mandl, K. D. Whose personal control? Creating private, personally controlled health records for pediatric and adolescent patients. J Am Med Inform Assoc 2008;737-43

McMurry, A. J., Gilbert, C. A., Reis, B. Y., Chueh, H. C., Kohane, I. S., and Mandl, K. D. A self-scaling, distributed information architecture for public health, research, and clinical care. J Am Med Inform Assoc 2007;527-33

Kohane, I. S., Mandl, K. D., Taylor, P. L., Holm, I. A., Nigrin, D. J., and Kunkel, L. M. Medicine. Reestablishing the researcher-patient compact. Science 2007;836-7

Mandl, K. D., Simons, W. W., Crawford, W. C., and Abbett, J. M. Indivo: a personally controlled health record for health information exchange and communication. BMC Med Inform Decis Mak 2007;25

Adida, B. and Kohane, I. S. GenePING: secure, scalable management of personal genomic data. BMC Genomics 2006;93

Simons, W. W., Mandl, K. D., and Kohane, I. S. The PING personally controlled electronic medical record system: technical architecture. J Am Med Inform Assoc 2005;47-54

Sax, U., Kohane, I., and Mandl, K. D. Wireless technology infrastructures for authentication of patients: PKI that rings. J Am Med Inform Assoc 2005;263-8

Kohane, I. S. and Altman, R. B. Health-information altruists—a potentially critical resource. N Engl J Med 2005;2074-7

Mandl, K. D., Szolovits, P., and Kohane, I. S. Public standards and patients’ control: how to keep electronic medical records accessible but private. BMJ 2001;283-7

Riva, A., Mandl, K. D., Oh, D. H., Nigrin, D. J., Butte, A., Szolovits, P., and Kohane, I. S. The personal internetworked notary and guardian. Int J Med Inform 2001;27-40

Peter Szolovits, Jon Doyle, William J. Long, Isaac Kohane, Stephen G. Pauker.  Guardian Angel: Patient-Centered Health Information Systems. Technical Report MIT/LCS/TR-604, Massachusetts Institute of Technology Laboratory for Computer Science, 1994.
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