Wagholikar KB, Jain R, Oliveira E, et al. Evolving Research Data Sharing Networks to Clinical App Sharing NetworksAMIA Summits on Translational Science Proceedings. 2017;2017:302-307.

ITdotHealth SMART Decisions, Executive Summaries. July 2017. © 2017 Harvard Medical School. Created by BullsEye Resources.

Kenneth D. Mandl, M.D., M.P.H., Isaac S. Kohane, M.D., Ph.D. A 21st-Century Health IT System — Creating a Real-World Information EconomyThe New England Journal of Medicine. Published online 18 May 2017. (doi: 10.1056/NEJMp1700235)

Perlin, J.B., Baker, D.B., Brailer, D.J., Fridma, D.B., Frisse, M.E., Halamka, J.D., Levi, J., Mandl, K.D., Marchibroda, J.M., Platt, R., Tang, P.C.  Information Technology Interoperability and Use for Better Care and Evidence. Vital Directions for Health and Health Care Series. Discussion Paper, National Academy of Medicine, Washington, DC. September 19, 2016.

Improving Cancer-Related Outcomes with Connected Health:
A Report to the President of the United States from the President’s Cancer Panel. Bethesda (MD): President’s Cancer Panel; 2016.

Wagholikar KB, Mandel JC, Klann JG, Wattanasin N, Mendis M, Chute CG, Mandl KD, Murphy SN. SMART-on-FHIR implemented over i2b2 Journal of the American Medical Informatics Association. Available online 6 June 2016. (doi:

Mandel JC, Kreda DA, Mandl KD, Kohane IS, Ramoni RB. SMART on FHIR: a standards-based, interoperable apps platform for electronic health recordsJournal of the American Medical Informatics Association. Available online 17 February 2016. (doi: 10.1093/jamia/ocv189 .)

Mandl KD, Mandel JC, Kohane IS. Driving Innovation in Health Systems through an Apps-Based Information EconomyCell Systems. Available online 11 June 2015. (doi: 10.1016/j.cels.2015.05.001.)

Mandl KD, Kohane IS. Federalist principles for healthcare data networks. Nature Biotechnology 33, 360–363 (2015). doi: 10.1038/nbt.3180

Alterovitz G, et al. SMART on FHIR Genomics: Facilitating standardized clinico-genomic apps. J Am Med Inform Assoc 2015;0:1–6. doi: 10.1093/jamia/ocv045, Brief Communication.

Mandl KD. Ebola in the United States: EHRs as a Public Health Tool at the Point of Care. JAMA. Published online October 20, 2014. (doi: 10.1001/jama.2014.15064.)

Sunyaev A, Dehling T, Taylor PL, Mandl KD. Availability and quality of mobile health app privacy policies. J Am Med Inform Assoc. Published Online First: 21 August 2014 (doi: 10.1136/amiajnl-2013-002605).

D’Amore JD, Mandel JC, Kreda DA, et al. Are Meaningful Use Stage 2 certified EHRs ready for interoperability? Findings from the SMART C-CDA Collaborative. J Am Med Inform Assoc. Published Online First: doi: 10.1136/amiajnl-2014-002883

Klann JG, McCoy AB, Wright A, Wattanasin N, Sittig DF, Murphy SN. Health Care Transformation Through Collaboration on Open-Source Informatics Projects: Integrating a Medical Applications Platform, Research Data Repository, and Patient Summarization. Interact J Med Res 2013;2(1):e11 (doi: 10.2196/ijmr.2454).

Kohane, I. S., and Mandl, K. D. Escaping the EHR Trap — The Future of Health IT [PDF]. N Engl J Med 2012 Jun 14;366(24):2240-2.

Mandl KD, Mandel JC, Murphy SN, Bernstam EV, Ramoni RL, Kreda DA, McCoy JM, Adida B, Kohane IS. The SMART Platform: early experience enabling substitutable applications for electronic health records [PDF]. J Am Med Inform Assoc. 2012 Jul-Aug;19(4):597-603. (doi: 10.1136/amiajnl-2011-000622)

Murphy, S. N., Weber, G., Mendis, M., Gainer, V., Chueh, H. C., Churchill, S., and Kohane, I. Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2). J Am Med Inform Assoc 2010;17:124-30

Weitzman E.R., Kaci, L., and D., Mandl K. Sharing Medical Data for Health Research: The Early Personal Health Record Experience. J Med Internet Res 2010;e14

Weber, G. M., Murphy, S. N., McMurry, A. J., Macfadden, D., Nigrin, D. J., Churchill, S., and Kohane, I. S. The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories. J Am Med Inform Assoc 2009;624-30

Weitzman, E. R., Kaci, L., and Mandl, K. D. Acceptability of a personally controlled health record in a community-based setting: implications for policy and design. J Med Internet Res 2009;e14

Mandl KD, Christensen C, Chueh H, Frisse M, Kibbe D, Kohane IS.  Ten Principles for Fostering Development of an “iPhone-like” Platform for Healthcare Information Technology

Kohane IS. Substitutability: Why, What and How? [PDF] Oct 5, 2009

Adida B. Open and Safe HIT Platforms [PDF] Sep 21, 2009

Mandl KD, Kohane IS. No small change for the health information economy. N Engl J Med. 2009 Mar 26;360(13):1278-81

Mandl, K. D. and Kohane, I. S. Tectonic shifts in the health information economy. N Engl J Med 2008;1732-7

Halamka, J. D., Mandl, K. D., and Tang, P. C. Early experiences with personal health records. J Am Med Inform Assoc 2008;1-7

Bourgeois, F. T., Simons, W. W., Olson, K., Brownstein, J. S., and Mandl, K. D. Evaluation of influenza prevention in the workplace using a personally controlled health record: randomized controlled trial. J Med Internet Res 2008;e5

Bourgeois, F. C., Taylor, P. L., Emans, S. J., Nigrin, D. J., and Mandl, K. D. Whose personal control? Creating private, personally controlled health records for pediatric and adolescent patients. J Am Med Inform Assoc 2008;737-43

McMurry, A. J., Gilbert, C. A., Reis, B. Y., Chueh, H. C., Kohane, I. S., and Mandl, K. D. A self-scaling, distributed information architecture for public health, research, and clinical care. J Am Med Inform Assoc 2007;527-33

Kohane, I. S., Mandl, K. D., Taylor, P. L., Holm, I. A., Nigrin, D. J., and Kunkel, L. M. Medicine. Reestablishing the researcher-patient compact. Science 2007;836-7

Mandl, K. D., Simons, W. W., Crawford, W. C., and Abbett, J. M. Indivo: a personally controlled health record for health information exchange and communication. BMC Med Inform Decis Mak 2007;25

Adida, B. and Kohane, I. S. GenePING: secure, scalable management of personal genomic data. BMC Genomics 2006;93

Simons, W. W., Mandl, K. D., and Kohane, I. S. The PING personally controlled electronic medical record system: technical architecture. J Am Med Inform Assoc 2005;47-54

Sax, U., Kohane, I., and Mandl, K. D. Wireless technology infrastructures for authentication of patients: PKI that rings. J Am Med Inform Assoc 2005;263-8

Kohane, I. S. and Altman, R. B. Health-information altruists—a potentially critical resource. N Engl J Med 2005;2074-7

Mandl, K. D., Szolovits, P., and Kohane, I. S. Public standards and patients’ control: how to keep electronic medical records accessible but private. BMJ 2001;283-7

Riva, A., Mandl, K. D., Oh, D. H., Nigrin, D. J., Butte, A., Szolovits, P., and Kohane, I. S. The personal internetworked notary and guardian. Int J Med Inform 2001;27-40

Peter Szolovits, Jon Doyle, William J. Long, Isaac Kohane, Stephen G. Pauker.  Guardian Angel: Patient-Centered Health Information Systems. Technical Report MIT/LCS/TR-604, Massachusetts Institute of Technology Laboratory for Computer Science, 1994.
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